The path to make transplantation and cellular therapies safer for patients

Wednesday, September 13th, 2023 | 11:00 AM - 12:00 PM CT

When it comes to transplantation and cellular therapies, there's always two key risks worrying clinicians and patients: Relapse of disease and treatment-related mortality. But timely and balanced immune reconstitution cuts these limitations significantly. 

Recently developed and validated population pharmacokinetic models make immune reconstitution predictable and has led to safer and more effective transplantation and cellular therapies. Join this session and learn from experts on how precision dosing makes TCT more effective. 

Learning points: 
  • Understand how timely and balanced immune reconstitution drives positive outcomes after hematopoietic cell transplantation
  • Outline an ideal preparative regimen prior to TCT that takes pharmacokinetics of agents used into account. 
  • Demonstrate how individualizing the conditioning, considering population-PK, makes immune reconstitution predictable, as the clinical outcome, and makes TCT safer and more effective.




Jaap Jan Boelens MD PhD-Memorial Sloan Kettering_headshot - Maddi Billings

Jaap-Jan Boelens, MD, PhD

Chief, Transplantation and Cellular Therapies;
Co-director, Immune Discovery and Monitoring Service, Lab Medicine
Memorial Sloan Kettering Cancer Center

Sirj Goswami, PhD

Sirj Goswami, PhD

CEO & Co-founder