Fusion rates under pressure: What 10 years of published evidence reveals
Smokers. Diabetic patients. Revision cases. Multilevel fusions. These are the patients where reliable fusion is hardest to achieve and where biologic selection carries the most weight.
A clinical evidence review brings together more than 10 years of published literature and 37 peer-reviewed studies on cellular bone matrix outcomes across complex orthopedic and reconstructive procedures.
In spine, one retrospective study reported a 91.7% fusion rate across 96 posterolateral fusion patients with diabetes, smoking history and prior pseudarthrosis. A multilevel ACDF study reported 92.9% fusion versus 84% with demineralized bone matrix, with improved Neck Disability Index scores.
Takeaways inside:
A clinical evidence review brings together more than 10 years of published literature and 37 peer-reviewed studies on cellular bone matrix outcomes across complex orthopedic and reconstructive procedures.
In spine, one retrospective study reported a 91.7% fusion rate across 96 posterolateral fusion patients with diabetes, smoking history and prior pseudarthrosis. A multilevel ACDF study reported 92.9% fusion versus 84% with demineralized bone matrix, with improved Neck Disability Index scores.
Takeaways inside:
- Reported fusion outcomes in smokers, diabetic patients, revision procedures and multilevel cases
- How fusion compared to demineralized bone matrix, autograft and rhBMP-2
- Clinical, economic and histological evidence across spine and complex reconstruction
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