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At Mayo Clinic Florida and UC San Diego Health, clinical leaders are reshaping this pattern with structured diagnostic stewardship programs — cutting inappropriate testing, preserving antimicrobial effectiveness and improving diagnostic accuracy. This whitepaper explores how leading organizations are pairing precision diagnostics with thoughtful governance to steer clinical decisions, and why formal stewardship programs are now essential for regulatory compliance and value-based care success. Read how health systems are addressing waste and risk with smarter diagnostic strategies backed by actionable workflows, real metrics and clinician buy-in. **Insights include:**   - How Mayo Clinic Florida reduced inappropriate C. diff testing by more than 83% and cut incidence by 41% - Common pitfalls of over-testing and codetection, and how top systems are preventing them - The business case for diagnostic stewardship: financial, regulatory and patient-centered ROI   Please fill out the form to download the whitepaper.  [![](https://www.beckershospitalreview.com/wp-content/themes/beckers-healthcare/assets/images/logo.png) Becker's Hospital Review | Healthcare News & Analysis](https://www.beckershospitalreview.com) ### Contact Us [1-800-417-2035](tel:180041720354) [becker@beckershealthcare.com](mailto:becker@beckershealthcare.com) - [RSS Feed](https://www.beckershospitalreview.com/rss-feeds/) - [LinkedIn](https://www.linkedin.com/company/asc-communications/) - [Facebook](https://www.facebook.com/@BeckersHospitalReview/) - [X](https://x.com/beckershr) - [YouTube](https://www.youtube.com/user/hospitalreview1) ### Other Becker’s Sites - [ASC](https://www.beckersasc.com/) - [Spine](https://www.beckersspine.com/) - [Dental](https://www.beckersdental.com/) - [Payer](https://www.beckerspayer.com/) - [Behavioral](https://www.beckersbehavioralhealth.com/) - [Physician](https://www.beckersphysicianleadership.com/) ### More Resources - [Events](https://conferences.beckershospitalreview.com/upcoming-events/) - [Whitepapers](https://www.beckershospitalreview.com/whitepapers/) - [Live Webinars](https://www.beckershospitalreview.com/webinar-types/upcoming-webinars/) - [OnDemand Webinars](https://www.beckershospitalreview.com/webinar-types/ondemand-webinars/) Copyright © 2026 Becker’s Healthcare. 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