Cryoneurolysis with iovera° for OA Knee Pain: Clinical Evidence & Experience in Pre-TKA and Non-Surgical Patients

Monday, August 15th, 2022 | 3:00 PM - 4:00 PM CT

Osteoarthritis (OA) knee patients require options to manage their knee pain. Many are chronically cycling through NSAIDs, injections and opioids. Others are delaying or awaiting surgery or may not be surgical candidates.
iovera° is a novel, handheld device that alleviates pain including OA knee pain through a mechanism known as cryoneurolysis, which applies intensely focused cold therapy to a specific nerve to interrupt its ability to transmit a pain signal. The iovera° treatment uses the body's natural response to cold to treat peripheral nerves and immediately reduce pain—without the use of drugs. Treatment with iovera° provides immediate non-opioid pain relief that can last up to 90 days, and in some cases longer, as the nerve regenerates over time.

This first installment of a 2-part webinar series reviews how cryoneurolysis with iovera° achieves long lasting pain control, the clinical data demonstrating its safety and efficacy and clinical experience and treatment techniques as performed by the clinician presenters.

Webinar Learning Points:
  • The iovera° system
  • Cryoneurolysis and how it achieves immediate pain relief
  • Superficial and deep genicular nerves associated with OA Knee Pain
  • Peer-reviewed studies defining clinical outcomes resulting from iovera° treatments
  • Techniques in using iovera°

For full indication and important Safety Information for iovera°, visit 



Gary Schwartz Headshot - Margo Vieceli

Gary S. Schwartz, MD, FASA

Co-Director, Anesthesiology Associates of Boro Park, LLP, Vice Chair, Department of Anesthesia, Maimonides Medical Center (Brooklyn, NY)

Christopher Varacallo Headshot - Margo Vieceli

Christopher Varacallo, DO, CAQSM, FAAFP

Penn Highlands Orthopedics and Sports Medicine (DuBois, PA)