Seeing Beyond the Signal: Imaging After a Positive MCED Test


Thursday, June 12th, 2025 | 11:00 AM - 12:00 PM CT

Following a positive multi-cancer early detection (MCED) test, imaging plays a critical role in localizing potential malignancies and guiding diagnostic resolution. This session will examine diagnostic resolution pathways, explore considerations around incidental findings, and review evidence to support safe and efficient diagnostic resolution in the context of MCED test result.

Learning Objectives
By the end of this webinar, participants will be able to:
 
  • Describe the diagnostic pathways available following a positive MCED test, including the role of imaging in cancer localization and confirmation of malignancy.
  • Evaluate the safety, efficiency, and clinical utility of imaging-based approaches in confirming positive MCED test results.
  • Identify best practices for managing incidental findings uncovered during imaging workups, with a focus on minimizing harm, patient anxiety, and unnecessary interventions.
  • Apply practical considerations for integrating MCED testing into multidisciplinary care workflows, including coordination between primary care, radiology, oncology, and specialty care for diagnostic resolution.

Presenters:

Elliot Fishman headshot - Kristelle Khazzaka

Elliot K. Fishman, MD

Elliot K. Fishman Professorship in Radiology
Professor of Radiology, Surgery, Oncology and Urology
Johns Hopkins Hospital

Tom Beer - Kristelle Khazzaka

Tomasz M. Beer, MD, FACP

Chief Medical Officer, Multi-cancer Early Detection, Exact Sciences

Xiting Headshot - Kristelle Khazzaka

Xiting Cao, PhD

Director, Health Economics and Outcomes Research, Exact Sciences